Implications of Contemporary Clinical Trials Series
نویسندگان
چکیده
منابع مشابه
New section in Circulation: implications of contemporary clinical trials.
We are pleased to announce to our readers the launch of a new section in Circulation. The purpose is to provide a perspective on contemporary clinical trials in cardiovascular medicine. These trials need not be published in Circulation but must fulfill a minimum set of criteria so as to allow a multidisciplinary discussion of the trial across at least three of the following domains: clinical pr...
متن کاملImplications of Contemporary Clinical Trials The Placement of Aortic Transcatheter Valve (PARTNER) Trial Clinical Trialist Perspective
For several decades, surgical aortic valve replacement (sAVR) has been considered the therapeutic gold standard for the treatment of severe aortic stenosis (AS). Severe AS is a progressive disease with a long latency period, and despite significant strides in medical therapy for numerous other forms of cardiovascular disease, little progress has been made in medical therapy for AS. The mechanic...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملImplications of Contemporary Clinical Trials Transcatheter Aortic Valve Implantation The Interventionist Vision
Percutaneous catheter-based interventions are an emerging area in the treatment of valvular heart disease. Percutaneous aortic balloon valvuloplasty was initially introduced by Cribier et al1 in 1985 for patients with severe calcific aortic stenosis. This technique results in moderate hemodynamic improvement and significant clinical improvement, but it is associated with significant periprocedu...
متن کاملContemporary clinical trials in acute respiratory distress syndrome.
respiratory distress syndrome (ARDS). Today, the treatment of patients with acute RDS remains supportive; the syndrome remains a problem that has defied a satisfactory solution since its description nearly a quarter of a century ago.’ The conference was sponsored by the Respiratory Distress Syndrome Foundation,* in conjunction with the Division of Lung Diseases of the National Heart, Lung and B...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation
سال: 2012
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.112.121251